Arizona Cardinals at San Francisco 49ers: Betting Trends, Sep 27, 2026 (NFL)
The Arizona Cardinals visit the San Francisco 49ers on September 27, 2026. Trey McBride has cleared 20+ receiving yards in 20 of the last 20 games (100%), the highest rate on either side. Every figure on this page is a count of settled games or a line a book posted. DataStreak does not produce picks. Updated September 20, 2026.
The posted line
At fanduel as of September 20, 2026: SF -8.5, total 48.5. A line is the number a book posted at that moment, shown as a fact about the market; it is not a forecast and it moves.
Previous meetings
Finished regular-season games between the two, this season and last, newest first.
| Date | Away | Home |
|---|---|---|
| 2025-11-16 | SF 41 | ARI 22 |
| 2025-09-21 | ARI 15 | SF 16 |
Arizona Cardinals: last 5 games
| Date | Opp | Result |
|---|---|---|
| 2026-09-13 | @ LAC | W 26-14 |
| 2026-01-04 | @ LAR | L 20-37 |
| 2025-12-28 | @ CIN | L 14-37 |
| 2025-12-21 | vs ATL | L 19-26 |
| 2025-12-14 | @ HOU | L 20-40 |
San Francisco 49ers: last 5 games
| Date | Opp | Result |
|---|---|---|
| 2026-09-10 | @ LAR | W 27-7 |
| 2026-01-03 | vs SEA | L 3-13 |
| 2025-12-28 | vs CHI | W 42-38 |
| 2025-12-22 | @ IND | W 48-27 |
| 2025-12-14 | vs TEN | W 37-24 |
Over each player's last 20 games, the highest clear rate at the lowest posted rung of each market. Counts of games, not projections; each name opens the player's own page.
ARI players clearing their prop lines most often
| Player | Market | Line | Cleared | Rate |
|---|---|---|---|---|
| Trey McBride | Receiving Yards | 20+ receiving yards | 20 of 20 | 100% |
| Trey McBride | Receptions | 2+ receptions | 20 of 20 | 100% |
| Marvin Harrison Jr. | Receiving Yards | 20+ receiving yards | 18 of 20 | 90% |
SF players clearing their prop lines most often
| Player | Market | Line | Cleared | Rate |
|---|---|---|---|---|
| Christian McCaffrey | Rushing Yards | 20+ rushing yards | 20 of 20 | 100% |
| Mike Evans | Receiving Yards | 20+ receiving yards | 19 of 20 | 95% |
| Christian McCaffrey | Receiving Yards | 20+ receiving yards | 19 of 20 | 95% |
Questions about Arizona Cardinals at San Francisco 49ers
How have the last meetings between the Arizona Cardinals and the San Francisco 49ers gone?
Of the last 2 regular-season meetings this season and last, the San Francisco 49ers won 2 and the Arizona Cardinals won 0. The most recent was SF 41, ARI 22 on November 16, 2025.
Which players in Arizona Cardinals at San Francisco 49ers clear their prop lines most often?
Trey McBride has cleared 20+ receiving yards in 20 of his last 20 games (100%); Trey McBride has cleared 2+ receptions in 20 of his last 20 games (100%), over each player's last 20 games at the lowest posted rung. Counts of games, not projections.
Are these ARI at SF numbers picks?
No. Every figure is a count of settled games or a line a book posted, shown with the games it comes from so the arithmetic is checkable. DataStreak does not produce picks. Updated September 20, 2026.
How these numbers are measured
A cover is a settled game where the final margin beat the closing spread; a push is a margin that landed on it. Previous meetings are finished regular-season games between the two teams. The prop rates count the games in which a player's stat reached the line over that player's last 20 games. A posted line is one book's number on one day. Nothing here is a projection.
Every NFL prop graded on this date: NFL player props, September 27, 2026. Both teams' full pages: Arizona Cardinals and San Francisco 49ers. The live board with every team and tonight's lines is the NFL ATS Radar. Every NFL player at a glance: NFL player prop hit rates, or read how the boards are built.